NARRATOR: Understanding your loved ones historical past of most cancers is vital for understanding your personal danger.
About 5 to 10 breast cancers out of 100 are due to a single gene and should run in your loved ones.
We get one set of genes from every of our mother and father. These genes are like directions, telling our our bodies the way to construct cells.
The genes mostly affected in hereditary breast most cancers are the breast most cancers 1 and breast most cancers 2 genes, referred to as BRCA1 and BRCA2. Usually, these genes maintain most cancers cells from rising.
However generally they mutate and don’t work correctly, which might result in most cancers.
Everybody has BRCA1 and BRCA2 genes, however solely about 1 in each 400 folks in the USA has a mutation in both of those genes.
If both of your mother and father has a BRCA gene mutation, you might have a 1 in 2 likelihood of getting the identical mutation.
Not everybody who has a BRCA gene mutation will get breast most cancers. However these mutations do enhance your danger, particularly of getting breast most cancers at a youthful age.
Different genetic mutations also can enhance your danger of breast most cancers, however they don’t appear to extend the chance as a lot as BRCA mutations.
Even in households and not using a recognized genetic mutation, there should still be a historical past of most cancers.
These circumstances might be attributable to environmental elements, akin to publicity to chemical substances or a genetic mutation that hasn’t been found but.
If your loved ones has a historical past of breast or ovarian most cancers, you and your loved ones members usually tend to have a BRCA1 or BRCA2 mutation.
Having this data helps you perceive your possibilities of growing breast most cancers.
Some teams have a better danger for a BRCA gene mutation than others, akin to Ashkenazi Jewish ladies and Latinas .
A genetic counselor may also help you determine what your loved ones historical past means in your private danger.
When you can’t change your genes, you may decrease your danger of getting breast most cancers.
Way of life decisions akin to limiting alcohol consumption, sustaining a wholesome weight and exercising repeatedly have all been proven to make a distinction.
Whereas speaking about breast most cancers with your loved ones might not be simple, it will be significant. The extra you understand about your genetic historical past, the extra you are able to do to handle your danger.
This useful resource was created with help from Merck.
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