A question within the ICMR examine on sudden deaths in Covid occasions : How can the management group can also be vaccinated ?

A question within the ICMR examine on sudden deaths in Covid occasions : How can the management group can also be vaccinated ?

November 22, 2023 by dr s venkatesan

Information: A uncommon massive scale examine from ICMR is making information even within the mainstream media. (https://indianexpress.com/article/health-wellness/covid-19-vaccines-sudden-deaths-risk-icmr-study-9036761/)

An off-the-cuff learn of the unique paper threw up some ideas.

India’s apex medical physique, ICMR, initiated a examine totally on sudden deaths amongst younger folks in covid occasions . The first intention of this examine was to seek out what causes sudden unexplained deaths . and likewise check the speculation that the deaths weren’t most likely associated to covid vaccination. The examine did show that. (I’m not an professional to evaluate the statistical validity and scrutiny of the examine. It’s too complicated a mannequin. Nonetheless, I do have a primitive question as proven within the title )

However, we anticipated a minimal revelation. What prompted these 729 deaths (filtered out of 29000 deaths) I perceive bodily post-mortem couldn’t be carried out in majority of deaths (Even in witnessed , in hospital deaths). So, the query stays . Is it sudden cardiac demise ? Is it sudden “non cardiac ” demise ? or can it’s a “non sudden” masquerading as sudden in any approach.

.A preformed speculation

Although this isn’t a hypothesis-proving examine, it’s obvious that the intention of the examine primarily revolves round eradicating the stigma and worry related to vaccination. (The truth that solely a fraction of sufferers, (lower than 2%,) have been hospitalized for COVID signifies that this examine primarily meant to check the chance of COVID vaccination, which was round 85% in each teams.) It is smart, for the examine group , they created an excellent methodology accordingly and not directly proved the speculation proper. As physicians and cardiologists, we wished additionally look into the info of what prompted these deaths by performing autopsies in all doable instances. The outcomes of those autopsies have to be identified.

Conclusion is honest

It’s conventional (and acceptable ) guilty the center for all unexplained sudden deaths. The examine means that heavy consuming, together with with intense bodily exercise within the background of constructive household historical past, is behind lots of the deaths. It’s a honest assumption that they’re all cardiac. Sudden neurological and pulmonary deaths are underneath reported. In reality lots of the SCD is an arrhythmic occasion originating from CNS or electro-ionic triggers in blood with the wholesome coronary heart

Is that this not a main limitation*

Whenever you need to know whether or not COVID vaccination is expounded to sudden demise in any approach , you should have management of people that had no vaccination. On this examine, each teams had practically 82-88 % vaccination. In reality, the management group had few % further vaccination, and this helped the examine, to assert that vaccination prevented a few of the sudden deaths. This appears far-fetched with any statistical methodology. This, I really feel is a critical limitation. It will probably even nullify the examine conclusion to a big extent. (Consultants please make clear , It might be a completely incorrect notion)

Closing message

It’s a landmark try to check the mysterious deaths amongst younger Indians in covid & submit covid occasions. On the finish of the day, an unexplained demise stays unexplained as a result of we couldn’t do post-mortem (In fact we’ve got discovered the identical identified threat components accountable , besides most likely new one vigorous bodily exercise , )