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Cymbalta Alternate options to Contemplate — Talkspace

Cymbalta Alternate options to Contemplate — Talkspace


Revealed on: 30 Nov 2023

Alternatives to Cymbalta

Cymbalta (duloxetine) is a typical antidepressant for treating despair and anxiousness. It’s additionally generally prescribed for diabetic peripheral neuropathy and different medical situations that trigger ache, like arthritis, fibromyalgia, and continual again ache. Cymbalta is in a category of medicine generally known as serotonin-norepinephrine reuptake inhibitors (SNRIs). SNRIs steadiness norepinephrine and serotonin ranges — neurotransmitters related to temper regulation and application — within the mind.

Whereas Cymbalta will be very efficient for some individuals, it’s not at all times the appropriate treatment for everybody. It would trigger undesirable Cymbalta unwanted side effects, antagonistic drug interactions, not be efficient in relieving signs, otherwise you may simply be on the lookout for pure alternate options to Cymbalta use. Holistic therapy choices have gotten extra interesting and acquainted, whether or not mixed with treatment or remedy or when used independently. 

No matter your motive is for trying into Cymbalta alternate options, we’re diving into all the things you could find out about pure cures and different medicine much like Cymbalta. 

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Various Drugs to Cymbalta

There are a selection of medicines that could be viable alternate options to Cymbalta for despair or different situations. Since each drug has distinctive traits, advantages, dangers, and unwanted side effects, exploring every possibility and checking with a healthcare supplier is significant earlier than switching from Cymbalta.

1. Lexapro 

Lexapro (escitalopram) is an alternative choice to Cymbalta that may be good for people who find themselves involved about Cymbalta’s results when used long-term. Lexapro is within the class of medicine known as selective serotonin reuptake inhibitors (SSRIs), which work by growing serotonin ranges within the mind to boost temper. There are a lot of facets to contemplate when taking a look at Cymbalta vs Lexapro.

Variations between Cymbalta and Lexapro: 

  • Cymbalta is a serotonin and norepinephrine reuptake inhibitor (SNRI) whereas Lexapro is a selective serotonin reuptake inhibitor (SSRI).
  • Cymbalta is FDA-approved to deal with extra situations than Lexapro.
  • There may be fewer antagonistic unwanted side effects of Lexapro than Cymbalta.
  • In some research, Lexapro was more practical in treating main depressive dysfunction (MDD).

Similarities between Cymbalta and Lexapro: 

  • Each can deal with main depressive dysfunction (MDD) and anxiousness
  • Each medicine shouldn’t be used with the rest that will increase serotonin ranges.
  • Cymbalta and Lexapro shouldn’t be used with NSAIDs or different medicine that may trigger bleeding.

2.Effexor (venlafaxine)

Effexor may be a very good choice to discover because it’s one of many medicine much like Cymbalta. As a result of they’re in the identical class of antidepressants — SNRIs — they work equally.

Nevertheless, it’s necessary to notice that Effexor could trigger vital blood strain adjustments in comparison with different antidepressants. So, monitoring your BP commonly and consulting a medical skilled when taking this drug is vital. 

Variations between Cymbalta and Effexor: 

  • Cymbalta is used to deal with extra medical situations.
  • Effexor will be an choice to deal with panic dysfunction and social anxiousness dysfunction.
  • Effexor is extra more likely to lower intercourse drive as a facet impact.
  • Cymbalta is stronger and can be utilized in decrease doses.
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Similarities between Cymbalta and Effexor: 

  • Cymbalta and Effexor are each SNRIs.
  • Each medicine can deal with MDD and generalized anxiousness dysfunction (GAD).
  • Shared unwanted side effects embody dry mouth, drowsiness, lack of urge for food, and nausea.
  • Neither drug ought to be used along with monoamine oxidase inhibitors (MAOIs).

3. Prozac (fluoxetine)

Prozac is a typical and common antidepressant treatment within the SSRI class of medicine. It’s prescribed to deal with main depressive dysfunction and obsessive-compulsive dysfunction. It’s additionally authorised to deal with the consuming dysfunction bulimia and panic dysfunction in adults.

Variations between Cymbalta and Prozac:

  • They’re in several lessons of medicine — Cymbalta is an SNRI and Prozac is an SSRI.
  • Prozac is authorised to deal with extra psychological well being situations.
  • Prozac can be utilized to deal with some disordered consuming situations.
  • Cymbalta is authorised to deal with ache associated to some medical situations, whereas Prozac just isn’t.

Similarities between Cymbalta and Prozac:

  • Cymbalta and Prozac can be utilized to deal with main depressive dysfunction.
  • Research counsel that each medicine have related efficacy and security outcomes.

4. Wellbutrin (bupropion)

Wellbutrin is an antidepressant authorised to deal with main depressive dysfunction (MDD) and seasonal affective dysfunction (SAD). It’s additionally prescribed for smoking cessation. Within the norepinephrine and dopamine reuptake inhibitors (NDRIs) class of medicine, Wellbutrin has a number of the similar antagonistic results as Cymbalta, together with the potential to trigger dry mouth, dizziness, issue sleeping or insomnia, and nausea. 

Variations between Cymbalta and Wellbutrin:

  • Cymbalta and Wellbutrin belong to totally different lessons of medicine.
  • Cymbalta may cause diarrhea and fatigue; Wellbutrin typically doesn’t.
  • Wellbutrin may be a greater possibility for individuals who expertise weight achieve on Cymbalta.

Similarities between Cymbalta and Wellbutrin:

  • Each medicine are used to deal with sure sorts of ache.
  • Each Cymbalta and Wellbutrin will be efficient in treating despair.
Drug Class of Medicine Treatable Situations Frequent Facet Results
Cymbalta (duloxetine) SNRI Main depressive dysfunction
Basic anxiousness dysfunction
Nerve ache attributable to diabetes
Continual muscle and joint ache
Fibromyalgia
Drowsiness
Constipation
Nausea
Dry mouth
Lack of urge for food
Elevated sweating
Lexapro (escitalopram) SSRI Main depressive dysfunction
Generalized anxiousness dysfunction
Dry mouth
Nausea
Problem sleeping
Confusion
Diarrhea or constipation
Headache
Sexual dysfunction
Dizziness or drowsiness
Effexor (venlafaxine) SNRI Melancholy
Generalized anxiousness dysfunction
Panic dysfunction
Social anxiousness dysfunction
Nausea
Dry mouth 
Dizziness 
Drowsiness
Constipation
Lack of urge for food
Blurred imaginative and prescient
Prozac (fluoxetine) SSRI Main depressive dysfunction
Obsessive-
compulsive dysfunction
Bulimia
Panic dysfunction
Bipolar despair
Nausea
Dizziness
Drowsiness
Lack of urge for food
Problem sleeping
sweating
Wellbutrin (bupropion) NDRIs Melancholy
Seasonal have an effect on dysfunction
Smoking cessation
Headache
Sweating
Sleep points
Dry mouth
Dizziness

Pure Alternate options to Cymbalta

Drugs like Cymbalta can work effectively for some individuals, however others may desire a pure various. Whether or not it’s to keep away from unwanted side effects or since you choose a holistic method, there are a number of non-pharmaceutical Cymbalta alternate options out there.

6. Omega-3 fatty acids

Omega-3 fatty acids are identified for coronary heart well being advantages and the flexibility to assist psychological well being. Omega-3s are vital to mind operate and efficiency, and a few analysis has proven they’ll cut back signs of despair. Omega-3s are discovered naturally in meals sources like salmon or they’re out there as dietary supplements.

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7. Vitamin D

Generally known as the sunshine vitamin, Vitamin D can enhance temper, which could make it a possible various to Cymbalta for despair. Research have discovered that folks with despair typically have low vitamin D ranges, so supplementing may assist.

8. L-theanine

L-theanine is a novel amino acid present in inexperienced tea leaves. It’s gained recognition lately because of the calming impact it could possibly have on the physique and thoughts. In analysis, l-theanine has been proven to be efficient in stress aid, temper enhancement, and improved sleep high quality.

9. Way of life adjustments 

Adjusting your life-style by specializing in wholesome habits could be a shocking various to Cymbalta that many individuals may not think about. Implement the next into your days to see when you discover a discount in depressive signs and anxiousness.

  • Work out commonly: Analysis exhibits that getting the center price up releases endorphins, generally known as the feel-good hormones. Even one thing so simple as strolling briskly day by day can enhance your temper.
  • Eat wholesome: Attempt to eat a balanced weight loss program stuffed with nutrient-rich meals. It might not treatment your despair, however it could possibly assist naturally elevate your temper.
  • Follow mindfulness: Aware actions like meditation and journaling can change your mindset and enhance your temper.
  • Search remedy: Numerous research have confirmed the improved efficacy of mixing remedy and drugs vs. utilizing one or the opposite alone.

“Remedy is a good way to develop perception into signs and prognosis. It helps to facilitate consciousness and understanding of the problems that the individual is going through. You can even be taught well being coping methods to assist handle signs. Typically treatment and remedy are mixed to deal with the individual and have a constructive end result.”

Talkspace therapist Bisma Anwar, LPC, LMHC

Issues for Switching to a Cymbalta Various

For those who’re contemplating switching from a drugs like Cymbalta to a unique drug or a holistic therapy plan, there are a number of necessary components to recollect. Discovering an acceptable various is just attainable if it suits your distinctive wants and targets for enchancment.

Contemplate the next:

  • Why do you need to transition from Cymbalta?
  • Do the unwanted side effects of the drug outweigh any constructive outcomes?
  • Have you ever talked to your physician about different medicines you’re presently taking?

“It is very important work carefully together with your psychiatrist when switching medicines to keep away from Cymbalta withdrawal. Talk about and be open about your signs and issues together with your suppliers so they’re conscious of how you might be doing.”

Talkspace therapist Bisma Anwar, LPC, LMHC

Discover the Proper Various with Talkspace 

For those who’re making an attempt to resolve whether or not to alter medicines or take a holistic method to your therapy plan — or when you’re interested in combining drugs with remedy or non-pharmaceutical therapy choices — Talkspace is right here. 

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Talkspace is an internet platform with a group of psychological well being professionals who can present remedy, prescriptions, and drugs administration.

We provide telehealth from the consolation of your house as you make vital choices about your treatment and therapy plan. Our group is right here that can assist you navigate the complexities of treatment adjustments.

Sources:

  1. Khan A, Bose A, Alexopoulos GS, Gommoll C, Li D, Gandhi C. Double-blind comparability of Escitalopram and duloxetine in??the??acute therapy of main??depressive dysfunction. Medical Drug Investigation. 2007;27(7):481-492. doi:10.2165/00044011-200727070-00005. https://pubmed.ncbi.nlm.nih.gov/17563128/. Accessed September 24, 2023.  
  2. Kıvrak Y, Güvenç TS, Akbulut N, et al. Accelerated hypertension after venlafaxine utilization. Case Studies in Psychiatry. 2014;2014:1-4. doi:10.1155/2014/659715. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190979/. Accessed September 24, 2023. 
  3. Eckert L, Lançon C. Duloxetine in contrast with fluoxetine and venlafaxine: Use of meta-regression evaluation for oblique comparisons. BMC Psychiatry. 2006;6(1). doi:10.1186/1471-244x-6-30. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1552056/. Accessed September 24, 2023.  
  4. Larrieu T, Layé S. Meals for temper: Relevance of dietary omega-3 fatty acids for despair and anxiousness. Frontiers in Physiology. 2018;9. doi:10.3389/fphys.2018.01047. https://www.frontiersin.org/articles/10.3389/fphys.2018.01047/full. Accessed September 24, 2023. 
  5. BIČÍKOVÁ M, DUŠKOVÁ M, VÍTKŮ J, et al. Vitamin D in anxiousness and affective issues. Physiological Analysis. Revealed on-line 2015. doi:10.33549/physiolres.933082.https://www.biomed.cas.cz/physiolres/pdf/64percent20Supplpercent202/64_S101.pdf. Accessed September 24, 2023.
  6. White D, de Klerk S, Woods W, Gondalia S, Noonan C, Scholey A. Anti-stress, behavioural and magnetoencephalography results of an L-theanine-based nutrient drink: A randomised, double-blind, placebo-controlled, crossover trial. Vitamins. 2016;8(1):53. doi:10.3390/nu8010053. https://www.mdpi.com/2072-6643/8/1/53. Accessed September 24, 2023.
  7. Basso JC, Suzuki WA. The results of acute train on temper, cognition, neurophysiology, and neurochemical pathways: A Evaluate. Mind Plasticity. 2017;2(2):127-152. doi:10.3233/bpl-160040. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928534/. Accessed September 24, 2023.
  8. How do I select between treatment and remedy? American Psychological Affiliation. 2017. Accessed September 24, 2023. https://www.apa.org/ptsd-guideline/patients-and-families/medication-or-therapy

Talkspace articles are written by skilled psychological health-wellness contributors; they’re grounded in scientific analysis and evidence-based practices. Articles are extensively reviewed by our group of medical consultants (therapists and psychiatrists of assorted specialties) to make sure content material is correct and on par with present business requirements.

Our aim at Talkspace is to supply essentially the most up-to-date, useful, and goal info on psychological health-related matters to be able to assist readers make knowledgeable choices.

Articles include trusted third-party sources which are both straight linked to within the textual content or listed on the backside to take readers on to the supply.

Talkspace psychological well being providers


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